Author

Anthony W Segal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Adam P Levine· 2 shared Michael R Duchen· 1 shared

Activity by Year

2014-2016 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersImmunology

Adam P Levine

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2 papers

Recent·Most cited

The NADPH oxidase and microbial killing by neutrophils, with a particular emphasis on the proposed antimicrobial role of myeloperoxidase within the phagocytic vacuole

Adam P Levine, Anthony W Segal

This review challenges the traditional view of NADPH oxidase function in neutrophils, proposing it optimizes vacuolar conditions for antimicrobial proteins rather than solely producing hydrogen peroxide.

Microbiology Spectrum · Aug 12, 2016Peer-reviewedImmunology

The HVCN1 channel conducts protons into the phagocytic vacuole of neutrophils to produce a physiologically alkaline pH

Adam P Levine, Michael R Duchen, Anthony W Segal

This study shows HVCN1 channels in neutrophils acidify the cytosol and alkalinize the phagocytic vacuole, essential for immune function.

bioRxiv · Mar 27, 2014Cell Biology