The HVCN1 channel conducts protons into the phagocytic vacuole of neutrophils to produce a physiologically alkaline pH
Adam P Levine, Michael R Duchen, Anthony W Segal
This study shows HVCN1 channels in neutrophils acidify the cytosol and alkalinize the phagocytic vacuole, essential for immune function.
bioRxiv · Mar 27, 2014Cell Biology