Paralogs with distinct phase behaviors broaden the in vivo stress response range of condensates
Jian Guan, Bikash Ranjan Sahoo, Tyler S. Brant, Pavithra Mahadevan, Antonia Brooks, Shyamal Mosalaganti, James C.A. Bardwell, Ursula Jakob
This study shows that paralogs H-NS and StpA form distinct condensates with different phase behaviors, enabling bacteria to adjust condensate stability for stress response.
bioRxiv · Oct 13, 2025 · PreprintBiochemistry