Author
Tyler S. Brant
University of MichiganORCID 0000-0001-9609-8273Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 11 mutual co-author links5 papers
Recent·Most cited
- BiochemistrybioRxivPreprint
Paralogs with distinct phase behaviors broaden the in vivo stress response range of condensates
Jian Guan, Bikash Ranjan Sahoo, Tyler S. Brant…·Ursula Jakob
This study shows that paralogs H-NS and StpA form distinct condensates with different phase behaviors, enabling bacteria to adjust condensate stability for stress response.
DOI 10.1101/2025.10.13.682129 - Cell BiologyCommunications BiologyPeer-reviewed
Rapid structural analysis of bacterial ribosomes in situ
Barrett M. Powell, Tyler S. Brant, Joseph H. Davis, Shyamal Mosalaganti
The paper develops a rapid in situ cryo-ET workflow for bacterial ribosome structure analysis, achieving sub-nm resolution in E. coli within 10 days.
- Molecular BiologybioRxivPreprint
Identification of a P62-TIF-IA axis that drives nucleolar fusion and the senescence associated secretory phenotype
Hazel C. Thoms, Tyler S. Brant, Katie Duckett…·Lesley A. Stark
This study identifies a p62-TIF-IA axis that drives nucleolar fusion and the senescence-associated secretory phenotype (SASP) through ATM-mediated disruption of autophagic degradation.
DOI 10.1101/2023.12.05.570133 - BioinformaticsbioRxivPreprint
Optimizing Polymerase Chain Reaction (PCR) using Machine Learning
Nicholas J. Cordaro, Andrew J. Kavran, Michael J. Smallegan…·Aaron J. Clauset
This study uses machine learning to improve PCR success rates, achieving 81% prediction accuracy and identifying 15 under-optimized features.