The Multi-scale Copula Index (MCI): a new information-theoretic measure of association and its applications in functional cancer genomics
Timothy Pham, Karina Meneses-Cime, Jiayan Ma, Bartholomew Tam, Amey Gupta, Michael R. Reich, Alex Wenzel, David Eby, Thorin T. Tabor, Helga Thorvaldsdóttir, Antony Castanza, Jill P. Mesirov, William Kim, Pablo Tamayo
The paper introduces the Multi-scale Copula Index (MCI), an information-theoretic measure of association, and demonstrates its utility in cancer genomics for capturing contextual associations in complex datasets.
bioRxiv · Oct 16, 2026 · PreprintBioinformatics