Glutamic Acid at position 168 is a constitutive activator of Tank Binding Kinase 1 catalytic function
Noopur Bhore, Anubhuti Sarkar, Zhi Yao, Susanne Herbst, Patrick Alfryn Lewis
The paper investigates the role of glutamic acid at position 168 in TBK1 kinase activity, finding it acts as a constitutive activator.
NeuroMolecular Medicine · Nov 5, 2025Peer-reviewedBiochemistry