NeurosciencebioRxivPreprint
Protein crosslinking as a therapeutic strategy for SOD1-related ALS
Md Amin Hossain, Richa Sarin, Daniel P. Donnelly…·Jeffrey N. Agar
This paper demonstrates that a cyclic thiosulfinate cross-linker stabilizes SOD1 variants in vivo, showing efficacy and low toxicity for treating SOD1-related ALS.
2 citations