ChAHP2 and ChAHP control diverse retrotransposons by complementary activities
Josip Ahel, Aparna Pandey, Michaela Schwaiger, Fabio Mohn, Anja Basters, Georg Kempf, Aude Andriollo, Lucas J. T. Kaaij, Daniel Heß, Marc Bühler
This study identifies ChAHP2, a protein complex that controls ERVs and LINEs by binding H3K9me3, and shows that ChAHP and ChAHP2 work together to repress retrotransposons.
bioRxiv · Feb 5, 2024Molecular Biology