Marc Bühler

The paper shows that CHD4 in the ChAHP complex antagonizes CTCF and silences transposons, while HP1 proteins are not required for these functions.

The paper identifies ChAHP as a repressor of SINE B2 elements by inhibiting TFIIIB recruitment, revealing a novel mechanism for controlling POL III-dependent transcription.

The paper identifies how cell heterogeneity and YAP1 inactivation drive tissue patterning during intestinal regeneration through feedback mechanisms.

The paper identifies how the HMD domain of Prf1 in the PAF1C complex activates HULC for H2B ubiquitination by repositioning its RING domains.

The paper creates a comprehensive atlas of transcription factor interactions in S. pombe using experimental methods and introduces a web tool for exploring the data.

This study identifies ChAHP2, a protein complex that controls ERVs and LINEs by binding H3K9me3, and shows that ChAHP and ChAHP2 work together to repress retrotransposons.

This study identifies NRDE2 and CCDC174 as RNA-binding proteins that enhance splicing of weak 5' splice sites by directly interacting with U1 snRNA in mouse ES cells.

The paper develops an automated deep learning pipeline to segment and classify yeast colonies, achieving 100x faster quantification than manual methods.