Daniel Heß

The paper shows that CHD4 in the ChAHP complex antagonizes CTCF and silences transposons, while HP1 proteins are not required for these functions.

The paper identifies MEP-1 as a novel substrate of DPF-3, showing cleavage after threonine and demonstrating its impact on reproductive fitness.

This study identifies novel components of the aggresome and characterizes their interactions during aggresome processing pathway dynamics in HeLa cells.

The paper identifies chromatin-dependent motif syntax that distinguishes binding patterns of NGN2 and MyoD1 during differentiation, revealing how context-specific chromatin states influence transcription factor specificity.

The paper creates a comprehensive atlas of transcription factor interactions in S. pombe using experimental methods and introduces a web tool for exploring the data.

This study identifies ChAHP2, a protein complex that controls ERVs and LINEs by binding H3K9me3, and shows that ChAHP and ChAHP2 work together to repress retrotransposons.

einprot provides an R package for reproducible analysis of quantitative proteomics data, generating reports with interactive visualizations and customizable workflows.

The paper identifies TRIM71's mechanism of mRNA silencing through recruitment of TNRC6/GW182 and shows competition among silencing pathways.

This study identifies NRDE2 and CCDC174 as RNA-binding proteins that enhance splicing of weak 5' splice sites by directly interacting with U1 snRNA in mouse ES cells.

This study identifies ZBTB2 as a btb-domain transcription factor that recruits chromatin remodelers and a histone chaperone during exit from pluripotency, revealing shared and unique functions of the btb-TF family.

This study identifies Hdac3 and Dax1 as repressors that restrict mESCs from transdifferentiating into extraembryonic endoderm by silencing Gata6 enhancers, while Nr5a2 and Esrrb promote this conversion.

The paper shows that proteolytic processing of Argonaute proteins by DPF-3 regulates small RNA association, maintaining genome integrity and fertility in C. elegans.