ECM (collagen) mediated signaling drives the emergence of androgen independence in prostate cancer cells
Apoorva Abikar, Prathibha Ranganathan
This study shows collagen in the tumor microenvironment promotes androgen independence in prostate cancer by enhancing cell migration, reducing chemotherapy sensitivity, and activating androgen receptor signaling through FAK.
Biochemistry and Biophysics Reports · Apr 18, 2026Peer-reviewedCancer Biology