REGENERATIVE GENE THERAPY IN THE HYPOTHALAMUS PROLONGS FERTILITY IN FEMALE RATS
Maria D. Gallardo, Mauricio Girard, Araceli Bigres, Marianne Lehmann, Silvia Susana Rodríguez, Rodolfo Gustavo Goya
This study shows that long-term hypothalamic gene therapy with Yamanaka factors extends fertility in middle-aged female rats by preserving ovarian function and cyclicity.
bioRxiv · May 24, 2023 · PreprintNeuroscience