Author

Maria D. Gallardo

Biochemistry Research Institute of La Plata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:rat· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

Marianne Lehmann· 3 shared Diana C. Pasquini· 2 shared Ezequiel LacunzaiD· 2 shared Juozas GordevičiusiD· 2 shared Martina Canatelli-MallatiD· 2 shared Mauricio Girard· 2 shared Priscila ChiavelliniiD· 2 shared Rodolfo G. Goya· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Marianne Lehmann

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3 papers

Recent·Most cited

COGNITIVE REJUVENATION IN OLD RATS BY HIPPOCAMPAL OSKM GENE THERAPY

Steve Horvath, Ezequiel Lacunza, Martina Canatelli-Mallat, Enrique Leo Portiansky, Maria D. Gallardo, Robert T. Brooke, Priscila Chiavellini, Diana C. Pasquini, Mauricio Girard, Marianne Lehmann, Yan Qi, Ake Tzu-Hui Lu, Amin Haghani, Juozas Gordevičius, Martı́n C. Abba, Rodolfo G. Goya

This study shows that OSKM gene therapy in old rats improves spatial learning and memory, reduces epigenetic age, and reverses age-related DNA methylation changes in the hippocampus.

GeroScience · Jul 22, 2024Peer-reviewedNeuroscience

REGENERATIVE GENE THERAPY IN THE HYPOTHALAMUS PROLONGS FERTILITY IN FEMALE RATS

Maria D. Gallardo, Mauricio Girard, Araceli Bigres, Marianne Lehmann, Silvia Susana Rodríguez, Rodolfo Gustavo Goya

This study shows that long-term hypothalamic gene therapy with Yamanaka factors extends fertility in middle-aged female rats by preserving ovarian function and cyclicity.

bioRxiv · May 24, 2023 · PreprintNeuroscience

YOUNG PLASMA REJUVENATES BLOOD DNA METHYLATION PROFILE, PROLONGS MEAN LIFESPAN AND IMPROVES HEALTH IN OLD RATS

Priscila Chiavellini, Martina Canatelli-Mallat, Marianne Lehmann, Joseph Alan Zoller, Juozas Gordevičius, Maria D. Gallardo, Diana C. Pasquini, Ezequiel Lacunza, Claudia Beatriz Hereñú, Gustavo R. Morel, Steve Horvath, Rodolfo G. Goya

This study shows that young rat plasma reduces DNA methylation age, extends lifespan, and improves health in old rats.

bioRxiv · Dec 1, 2022 · PreprintBioinformatics