Author

Ariel D. Lerner

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Molecular Biology· 1

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Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander J. ValvezaniD· 1 shared Alexandra N. GrumetiD· 1 shared Frank Scallo· 1 shared James H. Millonig· 1 shared Jay N. JoshiiD· 1 shared Paul G. Matteson· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Alexander J. ValvezanORCID

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1 paper

Recent·Most cited

mTORC1 activity oscillates throughout the cell cycle promoting mitotic entry and differentially influencing autophagy induction

Jay N. Joshi, Ariel D. Lerner, Frank Scallo, Alexandra N. Grumet, Paul G. Matteson, James H. Millonig, Alexander J. Valvezan

This study shows mTORC1 activity oscillates during the cell cycle, peaks in S and G2, and is lowest in mitosis and G1, with distinct regulatory mechanisms and functional consequences.

Cell Reports · Jul 26, 2024Peer-reviewedMolecular Biology