Author

Alexandra N. Grumet

ORCID 0009-0003-8820-4680Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander J. ValvezaniD· 1 shared Ariel D. Lerner· 1 shared Frank Scallo· 1 shared James H. Millonig· 1 shared Jay N. JoshiiD· 1 shared Paul G. Matteson· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperMolecular Biology

Alexander J. ValvezanORCID

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1 paper

Recent·Most cited

Molecular BiologyCell ReportsPeer-reviewedJul 26, 2024

mTORC1 activity oscillates throughout the cell cycle promoting mitotic entry and differentially influencing autophagy induction

Jay N. Joshi, Ariel D. Lerner, Frank Scallo…·Alexander J. Valvezan

This study shows mTORC1 activity oscillates during the cell cycle, peaks in S and G2, and is lowest in mitosis and G1, with distinct regulatory mechanisms and functional consequences.

25 citations

statistical modelexperimental assay

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