Donor Age Impairs Vasculogenic Potential of hiPSC-Derived Endothelial Progenitors
Bryce Larsen, Cody J. Callahan, Arshitha Rayanki, Sara Faulkner, Janet Zoldan
This study shows that donor age impairs the vasculogenic potential of hiPSC-derived endothelial progenitors, with older donor cells forming less functional vascular structures and showing epigenetic and transcriptomic differences.
bioRxiv · Jun 24, 2025 · PreprintBioengineering