MXRA8 promotes adipose tissue whitening to drive obesity
Wentong Jia, Rocky Giwa, John R. Moley, Gordon I. Smith, Max C. Petersen, Rachael L Field, Omar Abousaway, Arthur S. Kim, Sarah R. Coffey, Stella Varnum, Jasmine M. Wright, Xinya Zhang, Samantha Krysa, Irfan J. Lodhi, Nada A. Abumrad, , Jonathan R. Brestoff
This study identifies MXRA8 as a promoter of adipose tissue whitening that drives obesity, showing its role in reducing UCP1 expression and protecting against obesity in mice.
bioRxiv · Jan 31, 2024 · PreprintPhysiology