Nada A. Abumrad

Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts

The paper shows immune cells regulate circulating adipocyte extracellular vesicle levels by clearing EVs, with reduced clearance in obesity leading to increased circulating adipoEVs.

Extracellular vesicles from chylomicron-treated endothelial cells drive macrophage inflammation

This study shows that chylomicron-treated endothelial cells release extracellular vesicles that drive macrophage inflammation and lipid droplet formation.

Secretion and transfer of adipose lipoprotein lipase utilizes neutral sphingomyelinase 2 generated exosomes

This study identifies nSMase2-generated exosomes as a mechanism for adipocyte LPL secretion and transfer to endothelial cells via GPIHBP1.

Insulin regulates lymphatic endothelial function via palmitoylation

This study investigates how insulin regulates lymphatic endothelial function through palmitoylation, identifying CD36 as a mediator of this process.