Single Cell Transcriptome Signatures of Sarcoidosis in Lung Immune Cell Populations
Camille M. Moore, Shu‐Yi Liao, Cheyret Wood, Arunangshu Sarkar, Jonathan Cardwell, Kristyn MacPhail, Margaret M. Mroz, Christina Riley, Kara J. Mould, Clara I. Restrepo, Li Li, Lisa A. Maier, Ivana V. Yang
The paper identifies cell-specific molecular changes in sarcoidosis by analyzing single-cell RNA-seq data from lung immune cells, revealing distinct macrophage subpopulations and altered gene expression patterns associated with disease progression.
bioRxiv · Jan 20, 2025 · PreprintGenomics