Camille M. Moore

The paper introduces REBEL, a method for analyzing differential expression in longitudinal scRNA-seq data, showing it controls false discovery rate and has competitive power.

The paper develops statistical methods to adjust for nonignorable dropout in longitudinal studies with outcome-dependent sampling, using mixture models and the BUILD R package.

This study identifies and characterizes the anatomical distribution of human lung macrophage subpopulations using single-cell RNA sequencing and finds smoking-induced changes in their accumulation patterns.

This study investigates the physiologic recovery of Mycobacterium tuberculosis in mice after antibiotic treatment, finding that recovery is slow, sequential, and incomplete, with longer treatment leading to slower recovery.

The paper uses SEARCH-TB to analyze drug interactions in M. tuberculosis by measuring transcriptional responses to the BPaL regimen in vivo, showing complex effects of drug combinations.

The paper identifies cell-specific molecular changes in sarcoidosis by analyzing single-cell RNA-seq data from lung immune cells, revealing distinct macrophage subpopulations and altered gene expression patterns associated with disease progression.

This study examines how prolonged antibiotic treatment affects M. tuberculosis physiology in mice, finding that sterilizing and non-sterilizing antibiotics induce distinct transcriptional responses.

The paper introduces RESCUE, a method to simulate longitudinal scRNA-seq data, incorporating between-sample and between-subject variability, and demonstrates its use in study planning.

The paper compares transcriptomic profiles of CF probands and their parents to healthy controls, revealing CFTR-related immune dysfunction in both homozygous and heterozygous carriers.

This study uses a single-molecule platform to show that SNF2h, a chromatin remodeler, regulates DNA accessibility based on nucleosome density in vitro and in vivo.

This study presents the structure of the yeast RSC chromatin remodeler, revealing its core and flexible lobes and how it interacts with nucleosomes.