Kara J. Mould

The paper introduces REBEL, a method for analyzing differential expression in longitudinal scRNA-seq data, showing it controls false discovery rate and has competitive power.

This study identifies and characterizes the anatomical distribution of human lung macrophage subpopulations using single-cell RNA sequencing and finds smoking-induced changes in their accumulation patterns.

The paper identifies cell-specific molecular changes in sarcoidosis by analyzing single-cell RNA-seq data from lung immune cells, revealing distinct macrophage subpopulations and altered gene expression patterns associated with disease progression.

The paper introduces RESCUE, a method to simulate longitudinal scRNA-seq data, incorporating between-sample and between-subject variability, and demonstrates its use in study planning.