Mechanistic Links Between Metabolic Dysfunction-Associated Steatotic Liver Disease and Heart Failure with Preserved Ejection Fraction in a Mouse Model
Niveen Rweished, Yair Rokach, Elchanan Parnasa, Suzan Abedat, Aseel Bsoul, Dean Nachman, Offer Amir, Rifaat Safadi, Rabea Asleh
This study investigates how MASLD worsens HFpEF in mice by identifying inflammatory and metabolic pathways linking liver steatosis to diastolic dysfunction.
bioRxiv · Nov 2, 2025 · PreprintPhysiology