Mechanical History and Substrate Stiffness Shape Integrin-Mediated Endothelial Cell Behavior on Bioactive Hydrogels
Abbey Nkansah, Aashee Budhwani, Ashauntee Fairley, Aarushi Chowdary Yedalla, Adhwita Anand, Nicholas Grammer, Josephine B. Allen, Elizabeth Cosgriff‐Hernandez
This study shows that substrate stiffness promotes integrin expression and endothelialization, while mechanical history has a transient effect on cell behavior.
bioRxiv · Jul 29, 2026 · PreprintBioengineering