Elizabeth Cosgriff‐Hernandez

Mechanical History and Substrate Stiffness Shape Integrin-Mediated Endothelial Cell Behavior on Bioactive Hydrogels

This study shows that substrate stiffness promotes integrin expression and endothelialization, while mechanical history has a transient effect on cell behavior.

Off-the-Shelf Multilayer Vascular Grafts with Damage-Resistant Hydrogel Coatings Incorporating Integrin Targeting

This paper develops multilayer vascular grafts with damage-resistant hydrogel coatings that promote endothelialization and maintain thromboresistance, showing durability after sterilization and physiological loading.

Design of a Conductive Hydrogel Coating to Improve Catheter-Tissue Coupling in Radiofrequency Ablation

This study develops a conductive hydrogel coating for radiofrequency ablation catheters to improve tissue contact and energy transfer, reducing collateral damage and recurrence.

3D Microscale Mechanical Simulations of Hydrogel Coated Electrospun Meshes

This paper uses 3D microscale mechanical simulations to predict bulk mechanical properties of hydrogel-coated electrospun meshes, revealing non-affine deformations and stress-strain differences.

Co-Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

This study compares co-electrospinning and blend electrospinning of polycaprolactone and SIS for bone wrap fabrication, showing co-spun wraps improve handling, infection control, and angiogenesis.

Characterization of Sex-Based Differences in Integrin-Mediated Endothelial Cell Adhesion to Bioactive Hydrogels

This study identifies sex-based differences in integrin expression and endothelial cell adhesion to bioactive hydrogels, highlighting the need to consider biological sex in biomaterial design.

Advanced Manufacturing of Coil-Reinforced Multilayer Vascular Grafts to Optimize Biomechanical Performance

The paper develops a multilayer vascular graft with a polymeric coil to improve kink resistance while maintaining compliance, using advanced manufacturing and finite element modeling to optimize biomechanical performance.

A Computational Framework to Optimize the Mechanical Behavior of Synthetic Vascular Grafts

This paper develops a computational framework to optimize vascular graft design by balancing compliance and buckling resistance through finite element analysis and optimization.

Design of PEG-based hydrogels as soft ionic conductors

This study designs PEG-based hydrogels with ionic conductivity by optimizing salt concentration, water content, and network structure to achieve desired mechanical and conductive properties.