Carbonic anhydrase inhibition rescues heart function in the Tg2576 Alzheimer's mouse model by ameliorating cardiac amyloid-β pathology and neurotrophic signaling impairment.
Andrea Elia, Rafael Vázquez‐Torres, Ashley Carey, Madison Wolf, Varenya R Gade, Micaelly Alves, Silvia Fossati
This study shows that carbonic anhydrase inhibitors improve heart function in Alzheimer's mice by reducing amyloid-β and restoring neurotrophic signaling.
bioRxiv · Oct 9, 2026 · PreprintCell Biology