Co-release of opposing signaling molecules controls the escalation and release of aggression
Rachel E. Gatlin, Jordyn Gagon, Damhyeon Kwak, Sewon Park, Hailee Walker, Lo Kronheim, Thomas J. Everett, Ashley Covington, Michaela M. Fluck, Tobias Zickmund, Nicholas Alonzo Frost, Moriel Zelikowsky
The paper identifies that co-released opposing signaling molecules, Neurokinin B and GABA, from Tac2+ neurons in the mPFC control distinct phases of aggression escalation and release in mice.
bioRxiv · Mar 13, 2025 · PreprintNeuroscience