Lo Kronheim

Adolescent alcohol consumption produces long term alterations in response inhibition and orbitofrontal-striatal activity in a sex-specific manner

This study shows that adolescent alcohol exposure leads to sex-specific changes in response inhibition and orbitofrontal-striatal activity, with increased adult alcohol consumption in males.

Co-release of opposing signaling molecules controls the escalation and release of aggression

The paper identifies that co-released opposing signaling molecules, Neurokinin B and GABA, from Tac2+ neurons in the mPFC control distinct phases of aggression escalation and release in mice.