Functionally selective dopamine D1 receptor endocytosis and signaling by catechol and non-catechol agonists
Ashley N Nilson, Daniel E Felsing, Pingyuan Wang, Manish Jain, Jia Zhou, John Allen
This paper investigates how catechol and non-catechol dopamine D1 receptor agonists induce different signaling and endocytosis patterns, showing that functional selectivity impacts receptor internalization.
bioRxiv · Apr 15, 2024 · PreprintPharmacology & Toxicology