Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis
Erin E. Mulkearns-Hubert, Nicole Hajdari, Ellen S. Hong, Ashley P. Jacobs, Aymerick Gaboriau, Sophia Giltner, Gavin Tannish, Kristen E. Kay, Sabrina Z. Wang, Peter S. LaViolette, Daniel J. Silver, Christopher G. Hubert, Andrew Dhawan, Justin Durla Lathia
This study shows that Cx43 promotes glioblastoma cancer stem cell survival and self-renewal via a WNK1-c-MYC signaling pathway.
Cell Reports · Sep 1, 2025Peer-reviewedCancer Biology