Author

Peter S. LaViolette

Medical College of WisconsinORCID 0000-0002-9602-6891Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Allison K. LowmaniD· 2 shared Ana Valeria CastroiD· 2 shared Anna GolebiewskaiD· 2 shared Annemiek WalenkampiD· 2 shared Antonio IavaroneiD· 2 shared Bart A. WestermaniD· 2 shared David Ryan OrmondiD· 2 shared Emre KocakavukiD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Allison K. LowmanORCID

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Author profile →

4 papers

Recent·Most cited

Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis

Erin E. Mulkearns-Hubert, Nicole Hajdari, Ellen S. Hong, Ashley P. Jacobs, Aymerick Gaboriau, Sophia Giltner, Gavin Tannish, Kristen E. Kay, Sabrina Z. Wang, Peter S. LaViolette, Daniel J. Silver, Christopher G. Hubert, Andrew Dhawan, Justin Durla Lathia

This study shows that Cx43 promotes glioblastoma cancer stem cell survival and self-renewal via a WNK1-c-MYC signaling pathway.

Cell Reports · Sep 1, 2025Peer-reviewedCancer Biology

Tumor-initiating genetics and therapy drive divergent molecular evolution in IDH-mutant gliomas

Tamrin Chowdhury, C. Mircea S. Tesileanu, Emre Kocakavuk, Kevin C. Johnson, Joo-Ho Lee, Zeynep Erson-Omay, Chaewon Heo, Kenneth Aldape, Samirkumar B. Amin, Kevin J. Anderson, David M. Ashley, Jill S. Barnholtz‐Sloan, Daniel Jay Brat, Andrew R. Brodbelt, Ana Valeria Castro, , Roel G.W. Verhaak

This study identifies genetic changes in IDH-mutant gliomas that correlate with treatment response and tumor evolution using longitudinal genomic data from 206 patient samples.

bioRxiv · Jul 11, 2025 · PreprintCancer Biology

The epigenetic evolution of gliomas is determined by their IDH1 mutation status and treatment regimen

Tathiane Maistro Malta, Thaís S. Sabedot, Natalia S. Morosini, Indrani Datta, Luciano Garofano, Wies Vallentgoed, Frederick S. Varn, Kenneth Aldape, Fulvio D’Angelo, Spyridon Bakas, Jill S. Barnholtz‐Sloan, Hui Kong Gan, Mohammad Hasanain, Ann‐Christin Hau, Kevin C. Johnson, , Peter S. LaViolette

This study analyzes the epigenetic evolution of IDH1-mutant and IDH1-wildtype gliomas under treatment, showing IDHmut tumors undergo epigenomic changes resembling IDHwt tumors, with implications for treatment strategies.

Cancer Research · Dec 20, 2023Peer-reviewedGenomics

Radio-pathomic maps of cell density identify glioma invasion beyond traditional MR imaging defined margins

Samuel A. Bobholz, Allison K. Lowman, Michael Brehler, Fitzgerald Kyereme, Savannah R. Duenweg, John Sherman, Sean D. McGarry, Elizabeth J. Cochran, Jennifer Connelly, Wade M. Mueller, Mohit Agarwal, Anjishnu Banerjee, Peter S. LaViolette

This study develops a radio-pathomic model to predict cellularity in gliomas using MRI data, identifying hypercellular regions beyond traditional imaging margins.

bioRxiv · Apr 7, 2021 · PreprintNeuroscience