Author

Ashley R. Flory

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Azusa MatsubaraiD· 1 shared Cícera Regina LazzarottoiD· 1 shared Claire Greene Whitfield· 1 shared Elizabeth Urbina· 1 shared GaHyun LeeiD· 1 shared Jacqueline ChyriD· 1 shared Jian MaiD· 1 shared Muyu YangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Azusa MatsubaraORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Frequent, context-dependent effects of human genetic variation on Cas9 activity revealed by population-scale GUIDE-seq-2 and deep combinatorial CHANCE-seq profiling

Ashley R. Flory, Cícera Regina Lazzarotto, Yichao Li, Jacqueline Chyr, Muyu Yang, Varun Katta, Elizabeth Urbina, GaHyun Lee, Rachael K. Wood, Azusa Matsubara, Claire Greene Whitfield, Sara R. Rashkin, Jian Ma, Yong Cheng, Shengdar Q. Tsai

The paper uses population-scale GUIDE-seq-2 and CHANCE-seq to analyze how genetic variants affect Cas9 activity, finding frequent context-dependent effects on off-target sites.

bioRxiv · Feb 10, 2025 · PreprintGenomics