Author

Azusa Matsubara

St. Jude Children's Research HospitalORCID 0009-0007-1637-6386Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashley R. Flory· 1 shared Cícera Regina LazzarottoiD· 1 shared Claire Greene Whitfield· 1 shared Elizabeth Urbina· 1 shared GaHyun LeeiD· 1 shared Jacqueline ChyriD· 1 shared Jian MaiD· 1 shared Muyu YangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Ashley R. Flory

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintFeb 10, 2025

Frequent, context-dependent effects of human genetic variation on Cas9 activity revealed by population-scale GUIDE-seq-2 and deep combinatorial CHANCE-seq profiling

Ashley R. Flory, Cícera Regina Lazzarotto, Yichao Li…·Shengdar Q. Tsai

The paper uses population-scale GUIDE-seq-2 and CHANCE-seq to analyze how genetic variants affect Cas9 activity, finding frequent context-dependent effects on off-target sites.

14 citations

humanCRISPR screen

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