Chronic Mild Stress Impairs Hippocampal Myelination through SOX6-Dependent Dysfunction of Oligodendrocyte Lineage Cells
Andrey Bombin, Cynthia Martín-Jiménez, Shun Yan, Shalini Saggu, Weiwei Liu, Yeimy González‐Giraldo, Emily Dew, Feng Zhou, Hanrui Wu, Quansheng Du, Tae Jin Lee, Ashok Sharma, Wei Zhang, Huidong Shi, Kai Jiao, Qin Wang
This study identifies SOX6 as a key regulator of oligodendrocyte dysfunction under chronic stress, linking stress to myelination deficits through molecular mechanisms.
bioRxiv · May 31, 2026 · PreprintNeuroscience