Shun Yan

This study identifies SOX6 as a key regulator of oligodendrocyte dysfunction under chronic stress, linking stress to myelination deficits through molecular mechanisms.

The paper shows that DICER1 activity is essential for mitral valve development but not tricuspid valve development, revealing miRNA-mediated gene regulation as a differential mechanism.

This study shows that mitochondrial fission is essential for embryonic heart development by regulating ribosomal protein gene transcription through an AMPK-SIRT7-GABPB axis.