Chronic Cadmium Exposures and Hyperglycemia Additively Drive Mitochondrial Dysfunction in Hepatic Cells: Key Implications for MASLD Etiopathogenesis
Rahul Kumar, Ashwin Chinala, Li Chen, Sharina Palencia Desai, Marcus A. Garcia, Sarah J. Blossom, Matthew J. Campen, Rama R. Gullapalli
This study shows chronic cadmium exposure combined with hyperglycemia worsens mitochondrial dysfunction in liver cells, suggesting a role in MASLD development.
bioRxiv · Sep 13, 2025 · PreprintPharmacology & Toxicology