Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control.
James Boocock, Megan Leask, Yukinori Okada, Hirotaka Matsuo, Yusuke Kawamura, Yongyong Shi, Changgui Li, David Bruce Mount, Asim K. Mandal, Weiqing Wang, Murray J. Cadzow, Anna L. Gosling, Tanya J. Major, Julia A. Horsfield, Hyon K. Choi, , Tony Raymond Merriman
This paper identifies 15 novel serum urate loci and links them to 44 genes, revealing new molecular mechanisms of urate control through genomic and eQTL analysis.
Human Molecular Genetics · Jan 20, 2020Peer-reviewedGenetics