Megan Leask

The paper reports a rare splice-site variant in TNNT2 found in Oceanian ancestry individuals, highlighting the need for diverse genomic datasets to avoid misclassification of variants.

This paper uses local Bayesian regressions to identify genomic regions with significant genetic covariance between chronic kidney disease and hyperuricemia, finding both novel and previously reported shared loci.

This paper introduces SNVformer, a Transformer-based model for GWAS data that predicts gout from SNVs with 83% AUROC, showing promise for scalable genotype-phenotype association analysis.

The paper identifies a population-specific missense variant in CETP that lowers CETP activity and improves lipid profile, similar to loss-of-function mutations.

This paper identifies 15 novel serum urate loci and links them to 44 genes, revealing new molecular mechanisms of urate control through genomic and eQTL analysis.

The paper presents the milkweed bug genome and comparative analyses to study molecular evolution and feeding ecology in Hemiptera.