Author

Audrey C. Noguchi

National Heart, Lung, and Blood Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Chengyu LiuiD· 2 shared Danielle SpringeriD· 2 shared Elizabeth MurphyiD· 1 shared Fan ZhangiD· 1 shared Hiroko Ishiwata-EndoiD· 1 shared Hong San· 1 shared Jiro KatoiD· 1 shared Joel MossiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Chengyu LiuORCID

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2 papers

Recent·Most cited

Mutation of a single cysteine in CaMKIIδ protects the heart from ischemia-reperfusion Injury

Nathália Rocco Machado, Junhui Sun, Audrey C. Noguchi, Danielle Springer, Chengyu Liu, Elizabeth Murphy, Rodney L. Levine

This study shows that mutating Cys273 in CaMKIIδ prevents disulfide formation, protecting the heart from ischemia-reperfusion injury without affecting normal cardiac function.

bioRxiv · Apr 30, 2026 · PreprintBiochemistry

A PARP inhibitor, rucaparib, improves cardiac dysfunction in ADP-ribose-acceptor hydrolase 3 (Arh3) deficiency

Sachiko Yamashita, Xiangning Bu, Hiroko Ishiwata-Endo, Jiro Kato, Danielle Springer, Audrey C. Noguchi, Morteza Peiravi, Chengyu Liu, Fan Zhang, Zu‐Xi Yu, Randy Clevenger, Karen J. Keeran, Hong San, Martin J. Lizak, Joel Moss

This study shows that ARH3 deficiency causes cardiac dysfunction and that rucaparib, a PARP inhibitor, improves cardiac contractility and reduces infarct size in ARH3-deficient mice.

bioRxiv · Feb 7, 2023 · PreprintMolecular Biology