The NuA4 acetyltransferase and non-canonical chromatin-associated MRN/ATM activity temporally define senescence-associated secretory programs
Nicolas Malaquin, Audrey Carrier-Leclerc, Aurelie Martinez, Mireille Dessureault, Sabrina Ghadaouia, Jean-Philippe Coppe, Stephanie Nadeau, Guillaume Cardin, Judith Campisi, Francis Rodier
The paper shows that delayed recruitment of acetyltransferases and non-canonical DDR activity temporally define SASP in senescence.
bioRxiv · Sep 11, 2018 · PreprintCell Biology