Signals from the bone marrow B cell niches shape pre-leukemic fate in murine B cell acute lymphoblastic leukemia
Marjorie C. Delahaye, Simon Léonard, Jeoffrey Pelletier, Jérôme Destin, Florence Bardin, Mourad Ounis, Céline Monvoisin, Naïs Prade, Laurine Gil, Audrey Dauba, Pierre J. Milpied, Ahmed Amine Khamlichi, Éric Delabesse, Tony Marchand, Cyril Broccardo, , Stéphane J.C. Mancini
This study shows that signals from the bone marrow B cell niches influence pre-leukemic cell fate in murine B-ALL by altering proliferation and secondary mutation patterns.
bioRxiv · Feb 14, 2025 · PreprintCancer Biology