Ubiquitination of stalled ribosomes enables mRNA decay via HBS-1 and NONU-1 in vivo
Parissa C. Monem, Nitin Vidyasagar, Audrey L. Piatt, Enisha Sehgal, Joshua A. Arribere
This study identifies the role of ubiquitination on ribosomal proteins in No-Go mRNA Decay (NGD) in C. elegans, showing that ubiquitin tags signal mRNA degradation via HBS-1 and NONU-1.
bioRxiv · Nov 8, 2021 · PreprintMolecular Biology