Author

Joshua A. Arribere

University of California, Santa CruzORCID 0000-0002-2467-7791Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Assay:metagenomics· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Organism:yeast· 1

Frequent Co-Authors

Parissa C. MonemiD· 2 shared Alexander Maxwell BurroughsiD· 1 shared Audrey L. Piatt· 1 shared Enisha SehgaliD· 1 shared Lakshminarayanan AravindiD· 1 shared Makena N. PuleiD· 1 shared Marcus J. ViscardiiD· 1 shared Marissa L. Glover· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Parissa C. MonemORCID

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3 papers

Recent·Most cited

NMD targets experience deadenylation during their maturation and endonucleolytic cleavage during their decay

Marcus J. Viscardi, Joshua A. Arribere

The paper uses single-molecule sequencing to show NMD targets undergo endonucleolytic cleavage and deadenylation, with SMG-6 and SMG-5 playing key roles in cleavage and deadenylation respectively.

bioRxiv · Sep 29, 2023 · PreprintMolecular Biology

Ubiquitination of stalled ribosomes enables mRNA decay via HBS-1 and NONU-1 in vivo

Parissa C. Monem, Nitin Vidyasagar, Audrey L. Piatt, Enisha Sehgal, Joshua A. Arribere

This study identifies the role of ubiquitination on ribosomal proteins in No-Go mRNA Decay (NGD) in C. elegans, showing that ubiquitin tags signal mRNA degradation via HBS-1 and NONU-1.

bioRxiv · Nov 8, 2021 · PreprintMolecular Biology

NONU-1 encodes a conserved endonuclease required for mRNA translation surveillance

Marissa L. Glover, Alexander Maxwell Burroughs, Parissa C. Monem, Thea A. Egelhofer, Makena N. Pule, Lakshminarayanan Aravind, Joshua A. Arribere

The paper identifies NONU-1 as an endoribonuclease essential for translation surveillance pathways and shows its conservation across species.

Cell Reports · Mar 1, 2020Peer-reviewedMolecular Biology