Rules of engagement: determinants of chemokine receptor activation and selectivity by CCL27 and CCL28
Mian Huang, Aura F. Celniker, Rezvan Chitsazi, Douglas P. Dyer, Ariane L. Jansma, Irina Kufareva, Catherina L. Salanga, Tracy M. Handel
This study identifies N-terminal determinants of CCL27 and CCL28 receptor activation and selectivity by analyzing mutations and using AlphaFold models.
Journal of Biological Chemistry · Sep 19, 2025Peer-reviewedPharmacology & Toxicology