Douglas P. Dyer

The paper introduces a high-throughput SPR array to profile GAG-protein interactions, validating it with known proteins and identifying new interactions.

The paper introduces a streamlined method for analyzing GAG disaccharides using HILIC-MS/MS, applicable to diverse biological samples.

This study shows that airway macrophages have a glycocalyx that changes during viral infection, affecting their inflammatory response and repair.

The paper shows leukocytes express heparan sulfate glycocalyx, which is shed during psoriasis-like inflammation, promoting leukocyte migration into skin.

The paper shows that CCR2-driven monocyte recruitment reduces radiotherapy-induced intestinal toxicity by enhancing IL-17 production.

This study identifies N-terminal determinants of CCL27 and CCL28 receptor activation and selectivity by analyzing mutations and using AlphaFold models.

This study shows CXCL4 enters the brain via GAG-binding to BBB proteoglycans and promotes neurogenesis through GAG-mediated oligomerization.

This study identifies hallmark gene expression and metabolic profiles of type 2 activated human lung macrophages using primary tissue-derived cells.