Specialized enteric glial cells coordinate intestinal motility
Marissa A. Scavuzzo, Katherine C. Letai, Jeyashri S. Rameshbabu, Alka Tomar, Isha K. Shah, Naya S. Alsouss, William J. Wulftange, Yuka Maeno-Hikichi, Jesse J. Zhan, Bruce W. Armstrong, Haleigh Paolucci, Begüm Aydin, H. Elizabeth Shick, Aakash K. Shah, Calia P. Thompson, , Paul J. Tesar
The paper identifies specialized enteric glial cell subtypes in the mouse duodenum using single nucleus RNA-sequencing and spatial transcriptomics, showing one subtype's role in sensing force via PIEZO2 and its impact on gut motility.
bioRxiv · Jun 7, 2023 · PreprintNeuroscience