Katherine C. Letai

The paper uses snRNA-seq to analyze ileitis in SAMP mice, identifying stromal and epithelial transcriptional changes that mirror human CD, including Igf1 and Pcsk6 expression.

The paper identifies specialized enteric glial cell subtypes in the mouse duodenum using single nucleus RNA-sequencing and spatial transcriptomics, showing one subtype's role in sensing force via PIEZO2 and its impact on gut motility.

This paper introduces an adaptive closed-loop stimulation system that learns to generate specific neural activity patterns in real-time.

The paper shows that firing rate homeostasis in cultured mouse neurons occurs without activity-regulated transcription, challenging the hypothesis that transcription is required for this process.