Yuka Maeno-Hikichi

Specialized enteric glial cells coordinate intestinal motility

The paper identifies specialized enteric glial cell subtypes in the mouse duodenum using single nucleus RNA-sequencing and spatial transcriptomics, showing one subtype's role in sensing force via PIEZO2 and its impact on gut motility.

Chemical inhibition of pathological reactive astrocytes promotes neural protection

This study shows that inhibiting HDAC3 reduces pathological features of reactive astrocytes in vitro and in vivo, promoting neural protection in neurodegenerative diseases.

Therapeutic suppression of proteolipid protein rescues Pelizaeus-Merzbacher Disease in mice

This paper shows that reducing PLP1 expression in a mouse model of PMD improves myelination, motor function, and lifespan, supporting PLP1 suppression as a therapeutic strategy.