Landscape and mutational dynamics of G-quadruplexes in the complete human genome and in haplotypes of diverse ancestry
Nikol Chantzi, Shiau Wei Liew, Aurell Wijaya, Candace S. Y. Chan, Ioannis Mouratidis, Emilyane de Oliveira Santana Amaral, Yasin Uzun, Martin Hemberg, Karen M. Vásquez, Chun Kit Kwok, Ilias Georgakopoulos‐Soares
The paper maps G-quadruplexes across the human genome and haplotypes, showing their enrichment in repetitive regions and association with genomic instability and PRDM9 binding.
bioRxiv · Jun 17, 2025 · PreprintGenomics