Nikol Chantzi

HSeeker identifies and scores H-DNA-forming sequences using a three-part algorithm, providing genomic coordinates and stability scores for further analysis.

The paper analyzes STR distribution across 117,253 organisms, finding significant taxonomic variation and higher STR abundance in eukaryotic and viral genomes compared to bacteria and archaea.

The paper maps G-quadruplexes across the human genome and haplotypes, showing their enrichment in repetitive regions and association with genomic instability and PRDM9 binding.

ZSeeker detects potential Z-DNA-forming sequences in genomes with improved accuracy and accessibility through a Python package and web interface.

invertiaDB is a database of inverted repeats across 118,070 organisms, providing a centralized resource for searching, visualizing, and downloading inverted repeat data.

The paper identifies peptide sequences unique to specific taxonomic groups, revealing their evolutionary and functional significance across species and their potential in human health applications.

The paper identifies ribosomal DNA arrays as the most H-DNA rich element in the human genome using the T2T assembly, showing 42.65-fold enrichment compared to chance.

The paper analyzes inverted repeats across 118,065 genomes to study their distribution, frequency, and functional roles in genomic instability and evolution.

Quadrupia identifies and characterizes G-quadruplex sequences across 108,449 genomes, revealing taxonomic patterns and experimentally validating key structures.

kmerDB provides a database of genomic and proteomic sequence information, including kmers, quasi-primes, and primes, for 45,785 genomes and 22,386 proteomes.

The paper calculates the rarity of short nucleic and peptide sequences across genomes and proteomes, finds dipeptide rarity in peptides but not dinucleotides, and develops predictive models for sequence frequency.

This paper introduces frequentmers, a metagenomic feature for early disease detection, and applies it to identify liver cirrhosis with high accuracy using stool samples.