Author

Shiau Wei Liew

City University of Hong KongORCID 0000-0002-2424-9084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chun Kit KwokiD· 3 shared Ilias Georgakopoulos‐SoaresiD· 2 shared Ioannis MouratidisiD· 2 shared Karen M. VásqueziD· 2 shared Nikol ChantziiD· 2 shared Akshatha NayakiD· 1 shared Apostolos ZaravinosiD· 1 shared Aurell Wijaya· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersGenomics

Chun Kit KwokORCID

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3 papers

Recent·Most cited

Modification of RNAs in natural rG4 (MoRNiNG), A Database of RNA Modification Sites Associated with the Dynamics of RNA Secondary Structures

Yicen Zhou, Shanxin Lyu, Shiau Wei Liew, Xi Mou, Ian T. Hoffecker, Jian Yan, Yu Li, Chun Kit Kwok, Jilin Zhang

The paper introduces MoRNiNG, a database of RNA modification sites associated with RNA secondary structure dynamics, and validates the impact of modifications on G-quadruplex formation.

bioRxiv · Sep 11, 2025 · PreprintSystems Biology

Landscape and mutational dynamics of G-quadruplexes in the complete human genome and in haplotypes of diverse ancestry

Nikol Chantzi, Shiau Wei Liew, Aurell Wijaya, Candace S. Y. Chan, Ioannis Mouratidis, Emilyane de Oliveira Santana Amaral, Yasin Uzun, Martin Hemberg, Karen M. Vásquez, Chun Kit Kwok, Ilias Georgakopoulos‐Soares

The paper maps G-quadruplexes across the human genome and haplotypes, showing their enrichment in repetitive regions and association with genomic instability and PRDM9 binding.

bioRxiv · Jun 17, 2025 · PreprintGenomics

Quadrupia: Derivation of G-quadruplexes for organismal genomes across the tree of life

Nikol Chantzi, Akshatha Nayak, Fotis A. Baltoumas, Eleni Aplakidou, Shiau Wei Liew, Jesslyn Elvaretta Galuh, Michail Patsakis, Camille M. Moeckel, Ioannis Mouratidis, Saiful Arefeen Sazed, Wilfried M. Guiblet, Austin Montgomery, Panagiotis Karmiris-Obratański, Wang Guliang, Apostolos Zaravinos, , Ilias Georgakopoulos‐Soares

Quadrupia identifies and characterizes G-quadruplex sequences across 108,449 genomes, revealing taxonomic patterns and experimentally validating key structures.

bioRxiv · Jul 9, 2024 · PreprintGenomics